Impaired baroreflex function and arterial compliance in primary aldosteronism
نویسندگان
چکیده
منابع مشابه
Peripheral arterial stiffness in primary aldosteronism.
Aldosterone overproduction increases arterial wall stiffness by accumulation of different types of collagen fibres and growth factors. Our previous studies showed that central (aortic) arterial stiffness is increased in primary aldosteronism (PA) independently of concomitant hypertension and that these changes might be reversible after successful adrenalectomy. There is limited data available o...
متن کاملRenal function in primary aldosteronism.
Renal Function in Primary Aldosteronism To the Editor: We read the interesting article of Rossi et al1 investigating the involvement of the kidney in a large group of patients with primary aldosteronism (PA) who were recruited in a multicentric, Italian study. In these patients, the authors observed greater urinary albumin excretion (UAE) and higher prevalence of microalbuminuria than in essent...
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The present study was designed to investigate baroreflex control capacity of arterial pressure (AP) in the conscious Watanabe heritable hyperlipidemic (WHHL) rabbit. The control capacity of the baroreflex system was assessed with overall open-loop gain (G). Seven WHHL and 14 normal Japanese white rabbits were chronically implanted two catheters in the aortic arch through the left subclavian and...
متن کاملAbnormalities of renal function and circulatory reflexes in primary aldosteronism.
IN PATIENTS with autonomic insufficiency, rapid intravenous infusion of an isotonic solution of sodium chloride results in abnormally rapid renal excretion of both sodium and water.' An identical renal response to intravenous infusion of saline solution was obtained in a preliminary study of two patients with primary aldosteronism.2 In subsequent investigations of hyperaldosteronism of renal an...
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Cardiovascular autonomic dysfunction, such as orthostatic hypotension consequent to baroreflex failure and cardiac sympathetic denervation, is frequently observed in the synucleinopathy Parkinson's disease (PD). In the present study, the baroreceptor reflex was assessed in mice overexpressing human wildtype alpha-synuclein (Thy1-aSyn), a genetic mouse model of synucleinopathy. The beat-to-beat ...
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ژورنال
عنوان ژورنال: Journal of Human Hypertension
سال: 1999
ISSN: 0950-9240,1476-5527
DOI: 10.1038/sj.jhh.1000737